Life
Worm-like amphibians called caecilians have a mutation in a genetic sequence that’s critical for limb development, which could explain how they became limbless
By Jake Buehler
Worm-like amphibians known as caecilians may have lost their legs thanks to the same genetic tweaks that snakes have.
An analysis of the amphibians’ genomes suggests that caecilians and snakes – separated by hundreds of millions of years of evolution – converged on the same mutations when ditching their limbs. The findings provide insights into the genetic underpinnings of the evolution of limblessness.
The 200-some species of caecilian are totally limbless, and live secretive lives in tropical soils or waterways. They have small or nonexistent eyes and …
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