1 year ago
77
The first Moroccan-produced tests to diagnose breast cancer and leukaemia will become commercially available within months, cutting costs and waiting times for patients in the country and across Africa.
Most of the diagnostic kits for cancer and other diseases in Africa are expensive imports from outside the continent, usually from Europe and the US.
“The price of the kit can be double that of what it would cost to manufacture it locally. It is also a long process. It can take weeks or months for the kits to arrive,” said Hassan Sefrioui, an executive board member of the Moroccan Foundation for Advanced Science, Innovation and Research (MASciR), which developed the new tests.
Development of the cancer kits has been under way since 2010, Sefrioui said, and the leukaemia tests have already been used in Morocco on 400 people. Previously, all samples would have to be sent to France for analysis, prolonging and delaying treatment. “But with locally manufactured test kits, we can get results within hours,” he said.
Breast cancer is the most prevalent cancer in Morocco and a leading cause of death among women. While global survival rates for those diagnosed early is high, a large percentage of breast cancer cases in low- and middle-income countries, including Morocco, are detected at a later stage.
Africa’s reliance on imported tests, treatments and vaccines has been a pressing concern for health authorities on the continent since the Covid-19 pandemic. An estimated 70% of pharmaceutical products and up to 99% of vaccines used in African countries are imported.
A common condition
ShowThe human toll of non-communicable diseases (NCDs) is huge and rising. These illnesses end the lives of approximately 41 million of the 56 million people who die every year – and three quarters of them are in the developing world.
NCDs are simply that; unlike, say, a virus, you can’t catch them. Instead, they are caused by a combination of genetic, physiological, environmental and behavioural factors. The main types are cancers, chronic respiratory illnesses, diabetes and cardiovascular disease – heart attacks and stroke. Approximately 80% are preventable, and all are on the rise, spreading inexorably around the world as ageing populations and lifestyles pushed by economic growth and urbanisation make being unhealthy a global phenomenon.
NCDs, once seen as illnesses of the wealthy, now have a grip on the poor. Disease, disability and death are perfectly designed to create and widen inequality – and being poor makes it less likely you will be diagnosed accurately or treated.
Investment in tackling these common and chronic conditions that kill 71% of us is incredibly low, while the cost to families, economies and communities is staggeringly high.
In low-income countries NCDs – typically slow and debilitating illnesses – are seeing a fraction of the money needed being invested or donated. Attention remains focused on the threats from communicable diseases, yet cancer death rates have long sped past the death toll from malaria, TB and HIV/Aids combined.
'A common condition' is a Guardian series reporting on NCDs in the developing world: their prevalence, the solutions, the causes and consequences, telling the stories of people living with these illnesses.
Tracy McVeigh, editor
“Africa is over reliant and over dependent,” said Christian Happi, director of the African Centre of Excellence for Genomics of Infectious Diseases, at a health conference in Rwanda last month. “The continent was entirely dependent on the outside at the start of the pandemic. We could not even produce simple diagnostics.”
The conference discussed ways to increase Africa’s manufacturing capacity. Last year saw the launch of the African Pharmaceutical Technology Foundation to expand production, and plans to improve regulatory oversight through the African Medicines Agency (AMA) were approved in 2019.
“We still need a comprehensive strategy to support local manufactures,” said Yenew Kebede Tebeje, head of laboratory systems and networks at the Africa Centres for Disease Control, which has been cooperating with MASciR to make the Moroccan diagnostic kits available in other African countries. “This includes access to hard currency and raw materials as well as creating a conducive regulatory environment for the evaluation of diagnostics.”
This regulatory framework, said Tebeje, could be facilitated by the AMA once it is fully established. “We are working with the AMA to harmonise regulatory processes. So, for example, if a product is evaluated in Kenya there will be no reason for Ethiopia to do the same evaluation.”
During the pandemic, MASciR developed Covid diagnostic kits, which were sold in Senegal, Tunisia, Ivory Coast and Rwanda. Sefrioui said the cancer tests could also be available to those countries.
The initial costs to procure the cancer tests from MASciR may be more expensive than from non-African competitors, said Tebeje, because small companies have to import raw materials. “But what I’m envisioning is the long-term impact. When these companies become strong and expand their manufacturing capacity, we will get to see the cost benefits.” He said costs could be cut within three years.
English (US)